Vol. 1, Issue 1, Part A (2019)

Aim: To study the incidence of Orbital Lymphomas among the orbital Neoplasia. Materials and Methods: This is a Prospective interventional study conducted at the department of Oculoplasty and Orbital diseases of Sarojini devi eye hospital. The study period was from January 2005 to December 2008. All cases of Orbital Lymphomas on clinical and radiological suspicion were included in the study. Informed consent was obtained from all cases. Patients who didn’t give consent were excluded from the study. All cases were examined by an experienced Ophthalmologist using Slit lamp, Snellens chart, Direct and indirect Ophthalmoscope, Hertel’s Exophthalmometer. Incisional biopsy done in all cases and Histopathological diagnosis was established. Immuno histochemistry was done to further narrow down the diagnosis. Cases were referred to medical oncologist for chemotherapy. Results: Of 609 cases of Orbital neoplasia presented during the study period, 185 were of Orbital Lymphomas. 136 were males and 49 were females. Age distribution was from 40 years to 80 years. Maximum number of cases were seen in 6^th and 7^th decade. Among the four risk factors, the most common noted in this study was exposure to pesticides. Conclusions: There is steady rise in the incidence of Lymphomas. Exposure to pesticides was most common risk factors for development of Lymphomas. Next common risk factor was exposure ammonia based hair dyes and colors. Third common risk factors was immuno compromised status ie HIV positive. Immuno suppression organ transplant cases or chronic diseases like Rheumatoid arthritis and Sarcoidosis was the least common risk factor in our study.