Vol. 2, Issue 1, Part A (2020)

Introduction: Fungi are the organisms present everywhere in our environment. Invasive fungal rhinosinusitis is a condition in which we see mycotic infiltration of the mucosa of the nasal cavity and paranasal sinuses. Methodology: Hospital-based prospective observational study in which the diagnosis of the case is confirmed by taking a detailed clinical history, Ear Nose and Throat examination, and Diagnostic nasal endoscopy wherever required. Results: 23% of cases belong to the age group of 56-65 years, followed by 20% in the age group of 46-55 years and least being 2 cases (7%) in 26-35 years age group. No particular age group is significantly more. The incidence of the disease was more in the male population with a sex ratio of 1.1:0.9. Among the 30 cases, 53.3% of cases treated with lipid emulsion, and 46.6 % treated with Intravenous Amphotericin deoxycholate.76.6% of cases underwent endoscopic sinus surgery and debridement. Conclusion: Invasive fungal rhinosinusitis is a relatively rare disease with high morbidity and mortality. Diabetes mellitus is the most common risk facor. IFRS can be successfully treated with a combination of Endonasal surgery and antifungal agents.