Vol. 7, Issue 2, Part A (2025)

Background: Major salivary gland tumours are an uncommon type of tumours with a variety of morphologies. Due to ethnic and geographic diversity, the tumours' clinicopathological characteristics also vary.
Objective: To find out the malignancy among major salivary glands neoplasm.
Methods: This cross-sectional study was carried out at the Department of ENT and Head Neck Surgery at Dhaka Medical College Hospital, Dhaka from July 2019 to December 2020, for a period of one and a half years. A total of 44 consecutive patients with major salivary gland neoplasms of all ages and sexes were enrolled. A detailed history, physical examination, FNAC, CT scan, MRI, USG, and histological examination of the operated specimen were used to diagnose the neoplastic lesion.
Results: Maximum affected patients were in 3rd and 4th decade. Females (54.5%) were predominant than males (45.5%). Maximum patients were from rural area (59.1%). Maximum patients were poor (65.9%). Most commonly involved salivary gland was the Parotid gland (79.5%). Prevalence of malignancy was 31.8%. Frequency of malignancy in parotid gland was 31.4% and in sub-mandibular gland was 33.3%. Most common malignancy in major salivary glands neoplasm was Mucoepidermoid carcinoma (42.9%) followed by adenoid cystic (21.4%), Acinic cell carcinoma (14.3%), adenocarcinoma (14.3%) and carcinoma ex pleomorphic (7.1%).
Conclusion: Frequency of malignancy was 31.8% in major salivary glands neoplasm. Frequency of malignancy in parotid gland and sub-mandibular glands were 31.4% and 33.3% respectively.