Vol. 7, Issue 2, Part B (2025)

Background: Laryngeal cancer accounts for approximately one fourth of all head and neck cancer & about 2% of all body tumors& it is the tenth commonest cancer in Iraq. Possible treatment options for early stage laryngeal cancer with curative intent are either surgery or radiotherapy.

Objectives: The aim of this case series study is to identify the relationship between the parameters of the study with laryngeal cancer, and also to evaluate the local control rate of early stage laryngeal cancer after treatment with external beam radiotherapy.

Methods: a case series study of 41 patients (3 patients- Tis, 23 patients- T₁, 15 patients- T₂) treated with 3DCRT in Baghdad Radiotherapy and Nuclear medicine Center, Baghdad Medical City Complex, Baghdad, Iraq, during period between January 2017 & Dec 2020.

Results: The results of the study showed that the common age group were (56-65) yrs, most of them were males in 70.7%, cigarette smoking also were recorded in 70.7%, all cases were SCC (100%), majority were glottic cancer in 85.4%, most of cases were T₁ in 56.1%, most of cases were (grade 2) in 63.4%.

Regarding results of disease relapse; mean period of follow up was 25.95± 13.559 months, the relapse incidence was 12.2%, the site of relapse was local, mean time of relapse was 10.6±3.578, and relapse free survival for the patients in this study was 45.45±3.07 months. Local control according to T staging were Tis up to 100%, T₁ up to 79%, T₂ up to 75%.

Conclusion: Relapse free survival in this study was 45.45± 3.07 months, parameters had significant impact on relapse free survival were site, grade, stage, radiotherapy dose. Local control rates by radiotherapy were reaching up to 100% in Tis & up to 79% in T₁&up to 75% in T₂.